Clevidipino como antihipertensivo en la cirugía de feocromocitoma

Autor: C. Luis-García, E. Arbonés-Aran, L. Lorente-Poch, L. Trillo-Urrutia, C. Teixell-Aleu
Rok vydání: 2018
Předmět:
Zdroj: Revista Española de Anestesiología y Reanimación. 65:225-228
ISSN: 0034-9356
Popis: Pheochromocytoma is a catecholamine-producing tumour and laparoscopic adrenalectomy is its treatment of choice. During pneumoperitoneum insufflation and tumour handling there is a high risk of massive catecholamine release and hypertensive crisis. After tumour excision, severe arterial hypotension is a common effect, due to relative vasodilation and the residual effect of antihypertensive drugs. We report the case of a patient with pheochromocytoma who was treated with laparoscopic adrenalectomy. During surgical manipulation there was a sudden hypertensive peak that could be controlled quickly with clevidipine infusion. After tumour resection, clevidipine perfusion was stopped and there were no arterial hypotension episodes. Clevidipine is a new intravenous calcium antagonist with rapid onset of action and short half-life that has no residual effect and does not produce arterial hypotension after tumour resection. For these reasons, it can be a first-choice drug for this kind of surgery.
Databáze: OpenAIRE