Nile Tilapia Fish Skin, Scales, and Spine as Naturally Derived Biomaterials for Tissue Regeneration

Autor: Manoel Odorico de Moraes, Maria Elisa Quezado Lima-Verde, Luiz E. Bertassoni, Edmar Maciel Lima Júnior, Antonio Ernando Carlos Ferreira Junior, Vicente de Paulo Aragão Saboia, Paulo Goberlânio de Barros Silva, S. Prakash Parthiban, Ana Paula Negreiros Nunes Alves
Rok vydání: 2020
Předmět:
Zdroj: Current Oral Health Reports. 7:335-343
ISSN: 2196-3002
DOI: 10.1007/s40496-020-00286-y
Popis: This study aims to review the literature on the use of Nile tilapia-derived extracellular matrix (ECM) proteins as naturally derived scaffold material for tissue regeneration. Nile tilapia has emerged as a particularly relevant specie for the development of fish-derived biomaterials. The skin, scale, and spine of various fish species have been extensively demonstrated as a potential source of native ECM proteins for use in regenerative medicine. When compared to synthetic polymers, collagen-based biomaterials introduce some disadvantages due to their lower biomechanical stiffness and rapid biodegradation. However, collagen-based biomaterials continue to be one of the most highly investigated natural materials for bone regeneration. Studies have pointed to tilapia as a satisfactory source of collagen for its quality and cost benefit, with good responses in vitro and in vivo, especially studies involving the skin as the main source of production. For both soft and hard tissue regenerations, Nile tilapia skin is being considered as a good source of collagen. Other sources (scales and spine) are less addressed in comparison to skin, which in turn, brings more consistent perspective in relation to clinical use.
Databáze: OpenAIRE
Externí odkaz: