Chemo and diastereoselective conjugate addition of Grignard reagents on parthenin, a bioactive natural sesquiterpene lactone

Autor:	Jajula Kashanna, Rathod Aravind Kumar, Bethapudirr Rama Rao, Paramesh Jangili
Rok vydání:	2013
Předmět:	chemistry.chemical_classification Chemistry Straight chain Reagent Organic Chemistry Drug Discovery Organic chemistry Alkylation Sesquiterpene lactone Biochemistry Alkyl Conjugate
Zdroj:	Tetrahedron Letters. 54:1634-1637
ISSN:	0040-4039
Popis:	The conjugate addition on a natural bioactive pseudoguaianolide sesquiterpene lactone parthenin with various Grignard reagents leads to 13-C alkylated products chemo and diastereoselectively in fair overall yields. Compared with other Grignard reagents vinyl and smaller straight chain alkyl Grignard reagents gave better yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e3fad28d481d145ec219ed82a6d66837 https://doi.org/10.1016/j.tetlet.2012.12.043 Zobrazit plný text záznamu Full Text from ScienceDirect