Portal Hypertensive Gastropathy and its Association among the Patients with Decompensated Chronic Liver Disease
| Autor: | Madhu S. Patil, Hemamalini Gururaj, R. Shiva Kumar, Tukaram L. Chavhan, Shardul Ramineni |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Scholars Journal of Applied Medical Sciences. 11:900-904 |
| ISSN: | 2320-6691 2347-954X |
| Popis: | Background: Although portal hypertension remains the crucial factor for the development of PHG, other factors should be considered in the development and progression of this condition like hepatic function, oesophageal varices, type of hepatitis virus and hypersplenism as evidenced by haematological variables (Anemia, leucopenia and thrombocytopenia). Aim & Objectives: To study the frequency of portal hypertensive gastropathy and its correlation with haematological and biochemical parameters and other endoscopic findings. Materials and methods: A prospective, hospital based, time bound study of 100 patients, admitted with decompensated chronic liver disease (diagnosed based on the evidence of sonography criteria) in a tertiary care center. Patients aged > 18 years and above admitted in SDM medical college and hospital were considered, demographic data, physical examination was done, basic investigations, hematological, biochemical (renal function test and liver function test) , coagulation profile, serology were evaluated. Upper gastrointestinal endoscopy procedure was done and data was collected in a pre designed performa. Results: The frequency of PHG in our study was 64%.Presence of PHG had significant association with SBP, DBP, haemoglobin, TLC. We also found significant association between PHG and grade 1 and 3 of esophageal varices, gastric varices and erosive gastritis. Conclusion: The frequency of PHG was 64% in the studied group and the presence of PHG correlates with presence of esophageal varices, erosive gastritis and gastric varices suggesting a common pathophysiology. |
| Databáze: | OpenAIRE |
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