0630 A 4-Week Sleep Intervention that Advances and Stabilizes Sleep Timing Leads To Meaningful Improvements in Pain and Physical Function in People With Fibromyalgia

Autor: Helen Burgess, Sonal Bahl, Katelyn Wilensky, Emily Spence, Riley Jouppi, Muneer Rizvydeen, Cathy Goldstein, David Williams, Myra Kim, John Burns
Rok vydání: 2022
Předmět:
Zdroj: Sleep. 45:A276-A277
ISSN: 1550-9109
0161-8105
Popis: Introduction Fibromyalgia is characterized by chronic widespread pain, mood and sleep disturbance, and affects over 20 million Americans. Pharmacological treatments (antidepressants, antiepileptics, opioids) often have small treatment effects and adverse side-effects. Exercise therapy requires significant patient motivation, and psychotherapy requires specialized personnel. Here we report on a randomized clinical trial in which we tested a 4-week sleep-wake scheduling intervention with either a dim or bright daily 1 hour morning light treatment. Methods Fifty-four adults (52 females, 18-78 years) meeting ACR 2011 diagnostic criteria for fibromyalgia completed a 5-week protocol. In the first week each participant slept at home, ad lib, on their usual sleep schedule. Thereafter, they followed a fixed sleep schedule and a daily 1-hour morning light treatment (randomized to dim or bright light). The sleep schedule advanced each participant’s individual sleep-wake timing by no more than 1 hour, and focused on stabilizing sleep timing. Participants were monitored with wrist actigraphy throughout the study. Outcomes were assessed at baseline, 2 weeks and 4 weeks after the intervention. Results The 4-week intervention resulted in an average 36-minute advance in participants’ sleep timing in both groups (ps Conclusion Results suggest that 4 weeks of an advanced and stabilized sleep schedule can lead to meaningful improvements in pain and physical function in people with fibromyalgia. The addition of a bright vs. dim morning light treatment did not further increase symptom improvement. A reduction in depressive symptoms during the intervention may have contributed to the improvements in pain and physical function. Sleep-wake scheduling should be further explored as a potentially feasible, acceptable and effective adjunctive non-pharmacological treatment for fibromyalgia. Support (If Any) Grant awarded from NINR R21 NR016930.
Databáze: OpenAIRE
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