Nuclear analogs of β-lactam antibiotics 8. Stereospecific synthesis of a C-3 methoxylated monocyclic s-lactam

Autor:	William M. Bryan, Robert M. DeMarinis
Rok vydání:	1982
Předmět:	chemistry.chemical_compound Stereospecificity chemistry medicine.drug_class Stereochemistry Organic Chemistry Drug Discovery Antibiotics medicine Lactam Organic chemistry Antimicrobial Biochemistry
Zdroj:	Tetrahedron Letters. 23:731-734
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)86933-6
Popis:	Methoxylation of 1 (R = PhOCH2CO) occurred stereospecifically from the α-face as determined by x-ray crystallography to provide 2 which was converted to 4 whose in vitro antimicrobial activity was determined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e3e73f2e111310c2bb703bd997502b8a https://doi.org/10.1016/s0040-4039(00)86933-6 Zobrazit plný text záznamu