Interaction of Bacteriocin-Capped Silver Nanoparticles with Food Pathogens and Their Antibacterial Effect

Autor: Ranjana Pathania, Naveen Kumar Navani, R. K. Malik, Supriya Deepak Patil, Mahak Sapra, Tarun Kumar Sharma, Aradhana Chopra, Rekha Sharma
Rok vydání: 2012
Předmět:
Zdroj: International Journal of Green Nanotechnology. 4:93-110
ISSN: 1943-0906
1943-0892
DOI: 10.1080/19430892.2012.678757
Popis: With the emergence of multiple-drug-resistant pathogens, the antibacterial property of silver in colloidal form has emerged as a potential candidate for combating infectious diseases. A combination of antibacterial agents along with nanosilver could prove to be more potent due to broadened antibacterial spectrum with possibly lower doses. In the present study, a facile single-step green method of synthesizing silver nanoparticles functionalized with an antibacterial peptide from a food-grade lactic acid bacterium is reported. The synthesized enterocin-coated silver nanoparticles showed broad-spectrum inhibition against a battery of food-borne pathogenic bacteria without any detectable toxicity to red blood cells. The present results evince that a new category of biocide based on silver nanoparticles coated with food-grade antibacterials can be developed using simple methods.
Databáze: OpenAIRE