Nonfunctioning Ectopic Pituitary Adenoma Presenting as Epistaxis: A Report of Two Cases
| Autor: | KP Aravindan, Premkumar Sasi, Jacob Paul Alapatt, Aparna Govindan, Suma Radhakrishnan |
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| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | An International Journal of Otorhinolaryngology Clinics. 6:130-133 |
| ISSN: | 0975-6957 0975-444X |
| DOI: | 10.5005/jp-journals-10003-1175 |
| Popis: | Ectopic pituitary adenomas are uncommon lesions and are found along the migratory pathway of the Rathke's pouch. Sites reported include suprasellar region, clivus, sphenoid sinus, nasopharynx, third ventricle, petrous temporal bone, hypo thalamus, etc. Compared to intrasellar adenomas, a higher proportion of the ectopic examples are functional and most commonly produce adenocorticotropic hormone (ACTH). The authors report two cases of ectopic pituitary adenoma in the sphenoid sinus in two male patients 36 and 40 years old, presenting with epistaxis. Both the patients did not have any endocrine abnor malities. The clinical and imaging findings were suggestive of sinonasal malignancy. The final diagnosis was made after histopathological examination and immunohistochemistry for cytokeratin, chromogranin and pituitary hormones. The diagnosis of ectopic pituitary adenomas is difficult especially in those tumors that are nonfunctioning. After extensive literature search, we could find only six cases of nonfunctioning adenomas reported in the sphenoid sinus and in all these cases the correct diagnosis could be made only by histopathology.How to cite this articleGovindan A, Sasi P, Radhakrishnan S, Alapatt JP, Aravindan KP. Nonfunctioning Ectopic Pituitary Adenoma Presenting as Epistaxis: A Report of Two Cases. Int J Otorhinolaryngol Clin 2014;6(3):130133. |
| Databáze: | OpenAIRE |
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