Physical Activity Level and Colorectal Cancer Mortality
| Autor: | Gyu Jang Lee, Sun Ha Jee, Yejin Mok, Christina Jeon |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Colorectal cancer business.industry Proportional hazards model Hazard ratio Public Health Environmental and Occupational Health Rectum medicine.disease Gastroenterology Physical activity level Metabolic equivalent Surgery 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Internal medicine medicine 030212 general & internal medicine business Prospective cohort study Body mass index |
| Zdroj: | Asia Pacific Journal of Public Health. 28:638-647 |
| ISSN: | 1941-2479 1010-5395 |
| DOI: | 10.1177/1010539516661761 |
| Popis: | Physical activity has been shown to reduce colorectal cancer risk. However, the association of physical activity levels separately with colon and rectum cancer mortality is less clear. We included 226 089 Korean in a large prospective cohort study. We assessed the associations of physical activity levels (length, frequency, and intensity) with colon and rectum cancer mortality using Cox proportional hazards model. Men, but not women, who had regular physical activity showed a lower risk of death from colon cancer. The association for high intensity of physical activity was borderline significant in men (hazard ratio 0.67; 95% CI = 0.45-1.00 for >17.5 MET-hour/week). The associations were largely consistent among those aged 2, low high-density lipoprotein cholesterol, current smoker, and without hypertension or history of cardiovascular disease. In conclusion, higher length or intensity of physical activity decreased colon, but not rectum cancer mortality in men. Regular physical activity may have beneficial effects on colon cancer survival. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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