Lupus Nephritis and Pregnancy
| Autor: | Ioannis Papageorgiou, George E. Digenis, Nick S. Zerefos, Panayotis S. Kontessis, George Daskalakis, Aristides Antsaklis, Aristides P. Paraskevopoulos, Peter T. Karaiskakis |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Lupus anticoagulant
Pregnancy medicine.medical_specialty Proteinuria Anti-nuclear antibody medicine.diagnostic_test Obstetrics business.industry Lupus nephritis Antibody titer Obstetrics and Gynecology medicine.disease Titer immune system diseases Immunology Internal Medicine medicine medicine.symptom skin and connective tissue diseases business Partial thromboplastin time |
| Zdroj: | Hypertension in Pregnancy. 17:23-30 |
| ISSN: | 1525-6065 1064-1955 |
| DOI: | 10.3109/10641959809072235 |
| Popis: | Objective: To record fetal and maternal outcome in pregnancies with systemic lupus nephritis.Subjects: Twelve pregnancies in 11 women with lupus nephritis were studied. All patients were followed during the entire term of the pregnancy and for 6 months postpartum. The laboratory studies performed included antinuclear antibody titer (ANA), anti-DNA antibody titer, complement component levels (C3 and C4), lupus anticoagulant, anticardiolipin antibody, serum creatinine, 24-h urine protein, partial thromboplastin time, VDRL, and tests of hematopoietic and hepatic function.Main Outcome Measures: Antenatal and postnatal complications of lupus nephritis, proteinuria, hypertension, preterm delivery, birthweight, and perinatal mortality.Results: Twenty-five percent of pregnancies resulted in fetal loss, 58% in premature delivery, and 17% in term delivery. There were no neonatal deaths. All patients conceived during a period of clinical remission. Flares of systemic lupus erythematosus (SLE) occurred in four patien... |
| Databáze: | OpenAIRE |
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