One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles via Huisgen 1,3-dipolar cycloaddition catalysed by SiO2–Cu(I) oxide and single crystal X-ray analysis of 1-benzyl-4-phenyl-1H-1,2,3-triazole

Autor:	Rajni Kant, Manjulla Gupta, Satya Paul, Vivek K. Gupta, Monika Gupta
Rok vydání:	2014
Předmět:	1 2 3-Triazole One-pot synthesis Oxide chemistry.chemical_element General Chemistry Copper Cycloaddition Catalysis chemistry.chemical_compound chemistry Polymer chemistry 1 3-Dipolar cycloaddition Organic chemistry Monoclinic crystal system
Zdroj:	Monatshefte für Chemie - Chemical Monthly. 146:143-148
ISSN:	1434-4475 0026-9247
DOI:	10.1007/s00706-014-1285-7
Popis:	A one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles via Huisgen 1,3-dipolar cycloaddition reaction between terminal alkynes, benzyl/allyl/alkyl halides, and NaN3 in water at room temperature using silica-supported copper(I) oxide (SiO2–Cu2O) has been developed. Various supported copper(I) oxide catalysts have been tested for this reaction where silica-supported copper(I) oxide works well in this reaction. The catalyst being heterogeneous can be easily recovered at the end of reaction and can be reused making the process completely economical. A single crystal X-ray analysis of 1-benzyl-4-phenyl-1H-1,2,3-triazole has revealed that the compound crystallizes in the monoclinic space group P21. .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e3b3e395bd2d0da52aaa45b3f239768c https://doi.org/10.1007/s00706-014-1285-7 Zobrazit plný text záznamu Full text from SpringerLink