Second malignant neoplasm (SMN) in a cohort of early stage cancer survivors (ESCS) followed at Instituto Oncológico Henry Moore (IOHM) in the last 15 years

Autor:	Edgardo G. J. Rivarola, Dario Niewiadomski, Ernesto Gil Deza, Flavio Tognelli, Felipe G. Gercovich, Claudia Lorena Acuna, Eduardo L. Morgenfeld, N. Gercovich
Rok vydání:	2016
Předmět:	Oncology Cancer Research medicine.medical_specialty education.field_of_study business.industry Incidence (epidemiology) Population medicine.disease Primary tumor Surgery Early-stage cancer Median follow-up Internal medicine Cohort medicine Secondary tumors Stage (cooking) business education
Zdroj:	Journal of Clinical Oncology. 34:e13057-e13057
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2016.34.15_suppl.e13057
Popis:	e13057Background: The prolonged survival achieved when tumors are treated at early stages allows the diagnosis of a SMN in many patients during the follow up period.The following study aims to present the incidence of secondary tumors in a cohort of ESCS patients (Pt) followed at IOHM. Methods: A search of the IOHM database was carried out, looking for Pt that had been registered between 1/12/2000 and 1/6/2015 with early stage (0-I-II-III) tumors and had been followed for more than six months. Those with a SMN were identified. In all of these, the following was studied: Dx, detection (screening vs symptomatic), presentation (synchronic vs metachronic) and stage. Results: It was possible to find 12038 ESCS that met selection criteria. Population characteristics: Median age at Dx of primary tumor: 58 years (r 18-98y). Sex: male 4689 Pt (39%) / female 7335 Pt (61%). Median follow up was 40 months (r 6-183m). The table below shows primary tumors and most frequent SMN. In 476/556 Pt (86%), SMN was metachronic ...
Databáze:	OpenAIRE
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