Effects of galanin infusion on GH secretion and GHRH-induced GH release in prepubertal male lambs

Autor: Mario Baratta, Daniel Portetelle, C. Tamanini, H Coy David, Andrea Giustina, Robert Renaville, Roberta Saleri
Rok vydání: 1999
Předmět:
Zdroj: Small Ruminant Research. 33:231-237
ISSN: 0921-4488
DOI: 10.1016/s0921-4488(99)00025-5
Popis: The coexistence of galanin (GAL) with some classical neurotransmitters suggests that it may exert a role as a neuroendocrine modulator. The aim of this study was to investigate the GH response to porcine galanin (p-GAL) in prepubertal male lambs. In the experiments A and B the i.v. infusion of galanin (5 μg/kg) for 60 min was carried out alone (Experiment A) or combined with an i.m. injection of GHRH (0.5 μg/kg) 30 min after infusion (Experiment B); in the Experiment C, galanin (5 μg/kg) was infused for 300 min. Galanin infusion was not effective in increasing GH baseline levels ( P > 0.08); however galanin potentiated ( P
Databáze: OpenAIRE