Autor: Jézabel Rocher, Caroline Goupille, Florence Hallouin, Le Pendu J
Rok vydání: 1999
Předmět:
Zdroj: Glycoconjugate Journal. 16:681-684
ISSN: 0282-0080
DOI: 10.1023/a:1007199124074
Popis: Clones either strongly or barely expressing the Tn and Sialyl-Tn antigens were isolated from a rat colon carcinoma cell line. Expression of the antigens in normal rat tissues was very restricted and vaccination using Ovine Submaxillary Mucin as the immunogen could delay growth of the Sialyl-Tn positive cells, but not of the Sialyl-Tn negative cells in syngeneic rats. The model should be useful for testing new anti-Tn or Sialyl-Tn vaccination protocols.
Databáze: OpenAIRE