Synthesis and characterization of heteroleptic metal complexes of Isoniazid and Metformin
| Autor: | L. M. Durosinmi, Olawale Folorunso Akinyele, E. G. Fakola, Ayowole O. Ayeni, Temitope Adekunle Ajayeoba |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Metal ions in aqueous solution
Imine chemistry.chemical_element Infrared spectroscopy Zinc 030204 cardiovascular system & hematology 010402 general chemistry 01 natural sciences Copper 0104 chemical sciences 03 medical and health sciences Nickel Crystallography chemistry.chemical_compound 0302 clinical medicine chemistry Octahedral molecular geometry Cobalt |
| Zdroj: | Ife Journal of Science. 21:184 |
| ISSN: | 0794-4896 |
| DOI: | 10.4314/ijs.v21i3.15 |
| Popis: | Mixed ligand complexes of Metformin and Isoniazid have been synthesized and characterized by solubility studies, percentage metal analysis, UV-Vis spectroscopy, IR spectroscopy, magnetic moments and conductivity measurements. The infrared spectra revealed the coordination of the ligands to the metal ions [manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II)]. Meformin coordinated as a bidentate ligand via the imine nitrogen while isoniazid coordinated through its amino nitrogen (NH ) and carbonyl oxygen (C=O). The electronic 2 spectra and magnetic moments for the complexes strongly suggested a six coordinate octahedral geometry. The molar conductance values of the complexes are within the range 0.45-8.72 Ω-1 cm2 mol-1 , and this confirms the non-electrolytic nature of the complexes. |
| Databáze: | OpenAIRE |
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