CLOZAPINE-INDUCED DIABETIC KETOACIDOSIS: A CASE REPORT
Autor: | Soumya Mary Alex, P. Umadevi, Sabarish B, Vidya Menon, Dipu Ts |
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Rok vydání: | 2018 |
Předmět: |
Pharmacology
Pediatrics medicine.medical_specialty endocrine system diseases Diabetic ketoacidosis business.industry Insulin medicine.medical_treatment nutritional and metabolic diseases Pharmaceutical Science Schizoaffective disorder Type 2 diabetes medicine.disease Discontinuation Diabetes mellitus medicine Pharmacology (medical) business Adverse effect Clozapine medicine.drug |
Zdroj: | Asian Journal of Pharmaceutical and Clinical Research. 11:1 |
ISSN: | 2455-3891 0974-2441 |
DOI: | 10.22159/ajpcr.2018.v11i3.19140 |
Popis: | The objective of this study was to report a case of a person with psychiatric illness treated with clozapine presented with diabetic ketoacidosis (DKA). A clinical monitoring was done on a 38-year-old Indian man affected by schizoaffective disorder, bipolar type presented with DKA after 3 months of clozapine therapy (250 mg/day). After treatment of DKA and discontinuation of clozapine, the patient improved symptomatically, his blood sugar levels normalized and insulin requirements also decreased. This report thus highlights that clinicians should be vigilant about the potential risk of new-onset diabetes and DKA in patients taking clozapine and utilize appropriate clinical and laboratory monitoring early in the course of treatment to prevent serious adverse effects. |
Databáze: | OpenAIRE |
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