From domino to multicomponent: synthesis of dihydroisobenzofurans
Autor: | Elisabetta Rossi, Monica Dell'Acqua, Giorgio Abbiati, Diego Facoetti |
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Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Tetrahedron. 67:1552-1556 |
ISSN: | 0040-4020 |
DOI: | 10.1016/j.tet.2010.12.056 |
Popis: | A variety of substituted dihydroisobenzofurans can be easily synthesized in high yields by a one-pot three-component approach starting from o-bromoarylaldehydes, methanol, and terminal alkynes. The reaction occurs through an unprecedented cooperative palladium/base promoted coupling/addition/cyclization sequence. |
Databáze: | OpenAIRE |
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