Synthesis of 5,8-dimethoxynaphtho[2,3-c]furan-4(9H)-one
Autor: | Matthew J. Piggott, Dieter Wege |
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Rok vydání: | 2006 |
Předmět: | |
Zdroj: | Tetrahedron. 62:3550-3556 |
ISSN: | 0040-4020 |
DOI: | 10.1016/j.tet.2006.01.096 |
Popis: | The synthesis of the title compound, which shares its skeleton with a number of biologically active natural products, is described. The key steps are construction of a 3,4-disubstituted furan by a tandem Diels–Alder-retro-Diels–Alder reaction of an alkyne with 4-phenyloxazole, and an intramolecular Friedel–Crafts acylation. |
Databáze: | OpenAIRE |
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