Synthesis of 5,8-dimethoxynaphtho[2,3-c]furan-4(9H)-one

Autor: Matthew J. Piggott, Dieter Wege
Rok vydání: 2006
Předmět:
Zdroj: Tetrahedron. 62:3550-3556
ISSN: 0040-4020
DOI: 10.1016/j.tet.2006.01.096
Popis: The synthesis of the title compound, which shares its skeleton with a number of biologically active natural products, is described. The key steps are construction of a 3,4-disubstituted furan by a tandem Diels–Alder-retro-Diels–Alder reaction of an alkyne with 4-phenyloxazole, and an intramolecular Friedel–Crafts acylation.
Databáze: OpenAIRE