Status of mineral metabolism in patients with COVID-19 on admission to the hospital

Autor: A. M. Gorbacheva, E. V. Kovaleva, I.S. Maganeva, E. E. Bibik, A. K. Eremkina, A. R. Ajnetdinova, Natalia Mokrysheva
Rok vydání: 2020
Předmět:
Zdroj: Profilakticheskaya meditsina. 123:64
ISSN: 2305-4948
DOI: 10.17116/profmed20202308164
Popis: Increasingly, there is evidence of the association of mineral metabolism with COVID-19, in particular states such as hypocalcaemia, vitamin D deficiency, which may weigh up the course of a new coronavirus infection Objective Evaluate the basic parameters of mineral metabolism in patients with COVID-19 of different severity at admission to the hospital Material and methods A single-center study was carried out at the Endocrinology Research Centre, Moscow Analysis of the mineral metabolism parameters, as well as clinical and instrumental assessment of the COVID-19 severity before specific immunotherapy was performed in 60 patients Results The frequency of hypocalcemia (according to the level of albumin-adjusted calcium) and vitamin D deficiency/insufficiency in the study group was 36 7 and 95%, respectively Lower saturation (SpO2) was observed in the subgroup with a lower level of 25(OH)D (p=0 001) and calcium (p=0 002) Patients with severe COVID-19 pneumonia (computer tomography (CT) scan grade 3-4) compared with those with less changes (CT grade 1-2) had significantly lower total calcium and albumin (p
Databáze: OpenAIRE