| Popis: |
Hairs are encountered commonly in a forensic investigation and can be a source of DNA. The amount of DNA within a single hair is often less than the optimal amount required for nuclear DNA markers. Most of the DNA is within a root sheath with trace amounts of mitochondrial DNA in the shaft. Nuclear DNA testing targets highly repetitive DNA regions called microsatellites. The quantity of starting template required for nuclear DNA profiling is 1 ng, which may be present in the root sheath but not within the hair shaft. Mitochondrial loci are targeted on hair shafts due to their greater copy number. |
