Electrophysiologic effects of mental stress in healthy subjects
| Autor: | Per Insulander, Hans Vallin, Anders Juhlin-Dannfelt M.D., Ulla Freyschuss M.D. |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Heart disease business.industry Hemodynamics Ventricular tachycardia medicine.disease Electrophysiology Epinephrine Internal medicine Anesthesia Ventricular fibrillation cardiovascular system medicine Cardiology cardiovascular diseases Electrical conduction system of the heart Cardiology and Cardiovascular Medicine business Stroop effect medicine.drug |
| Zdroj: | Journal of Electrocardiology. 36:301-309 |
| ISSN: | 0022-0736 |
| DOI: | 10.1016/s0022-0736(03)00078-5 |
| Popis: | Mental stress has been associated with serious cardiac arrhythmias, including ventricular tachycardia and ventricular fibrillation. The purpose of this study was to assess cardiac electrophysiologic effects of mental stress and compare them with those of epinephrine infusion. Ten healthy male volunteers participated. Electrophysiologic and hemodynamic variables were measured at baseline, during mental stress produced by Stroop’s color word conflict test and during epinephrine infusion at 2 rates (0.025 μmol/kg/min and 0.3 μmol/kg/min). Mental stress produced significant effects on the electrophysiologic properties of the heart with shortening of all measured electrophysiologic variables except atrial, most markedly those of the sinus and the atrioventricular nodes. The effects on the right ventricular myocardium and the His-Purkinje conduction system were less pronounced. During infusion of epinephrine, corresponding effects could only be reproduced at a much higher plasma level. Circulating epinephrine apparently plays a minor role as a mediator of mental stress effects on the heart. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect