N-adamantyl derivatives of arylamides of α-azacycloalkanecarboxylic acids and their topical anesthetic activity
Autor: | A. P. Skoldinov, I. V. Chernyakova, N. I. Avdyunina, V. M. Pyatin, A. S. Lebedeva, A. M. Likhosherstov, N. V. Klimova |
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Rok vydání: | 1995 |
Předmět: | |
Zdroj: | Pharmaceutical Chemistry Journal. 29:115-118 |
ISSN: | 1573-9031 0091-150X |
DOI: | 10.1007/bf02226522 |
Popis: | A series of arylamides of α-[N-adamantylpyrrolidyl-(or piperidyl)]carboxylic acids was obtained by reacting 1-(or 2-)aminoadamantanes with arylamides of α,Ω-dihalovaleric (or caproic) acid. The compounds exhibited a pronounced anesthetic activity in experiments. |
Databáze: | OpenAIRE |
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