| Autor: |
Teru Okitsu, Tetsuro Kawanishi, H. Shibata, Shoji Takeuchi, Yun Jung Heo |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
2011 16th International Solid-State Sensors, Actuators and Microsystems Conference. |
| DOI: |
10.1109/transducers.2011.5969342 |
| Popis: |
Fluorescence-based implantable glucose sensors can provide continuous glucose monitoring (CGM) with wireless transdermal transmission and long-lasting activity in vivo. Here, we present a long-term in vivo glucose monitoring method using glucose-responsive fluorescent hydrogel fibers. The fiber structure enables the sensor to remain at an implantation site for a long period and be removed from the implantation site after use. We found that the polyethylene glycol (PEG)-bonded polyacrylamide (PAAm) hydrogel fibers reduced inflammation, transdermally glowed and continuously responded to blood glucose concentration changes after 2.5 months, showing their potential application for long-term in vivo continuous glucose monitoring. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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