Investigation of chimerism in a healthy, adult female by means of minisatellite and microsatellite typing

Autor: R.B.K. Reisacher, Gerhard Lanzer, W. R. Mayr, E.M. Dauber, B. Glock, S.O. Rennhofer, Thomas Wagner, D. Tröscher, S. Stadlbacher
Rok vydání: 2003
Předmět:
Zdroj: International Congress Series. 1239:561-563
ISSN: 0531-5131
DOI: 10.1016/s0531-5131(02)00298-4
Popis: DNA profiles were generated from blood and a tissue sample (buccal swab) of a healthy female showing irregular agglutinations in serological blood grouping and from whole blood samples of her parents in order to prove the presumption of chimerism and differentiate between its different forms. Genetic patterns of different cell types, including double maternal and paternal contribution of alleles at some loci, could be detected in whole blood and the buccal swab sample. Thus, the chimerism detected in the proposita was not restricted to the blood.
Databáze: OpenAIRE