Impact of Continuous Glucose Monitors’ Accuracy on Their Clinical Utility—A Quantitative Assessment
| Autor: | Didier Morel, Damian Bialonczyk, Christopher J. Koziel, James Petisce, Drilon Saliu |
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| Rok vydání: | 2018 |
| Předmět: |
Research design
medicine.medical_specialty business.industry 030503 health policy & services Endocrinology Diabetes and Metabolism Outcome measures MEDLINE 03 medical and health sciences 0302 clinical medicine Emergency medicine Internal Medicine Quantitative assessment Medicine In patient 030212 general & internal medicine Clinical efficacy Glucose monitors 0305 other medical science business |
| Zdroj: | Diabetes. 67 |
| ISSN: | 1939-327X 0012-1797 |
| Popis: | Objective: Accuracy is recognized as an important attribute of continuous glucose monitors (CGMs). The objective of this research was to understand if improvements in CGM accuracy impact clinical outcomes in patients with T1DM or T2DM. Research Design and Methods: A review of literature published from January 1999 to June 2017 was conducted using Medline. Articles were included if they reported desired outcome measures of clinical efficacy (HbA1c reduction, time-in-range [TIR], hypoglycemia detection or reduction) regardless of patient diabetes type. Simple linear and multiple regressions were utilized to evaluate the relationship between mean absolute relative difference (MARD) and measures of efficacy. Results: The literature search yielded 574 results from which 20 articles met the inclusion criteria. MARD for commercialized CGM devices improved, on average, 0.75% per year (R2=0.87, p Conclusion: CGM accuracy correlates with an increased detection of hypoglycemic events, but not with HbA1c reduction. Disclosure C.J. Koziel: None. D. Bialonczyk: Employee; Self; Becton, Dickinson and Company. D. Morel: Employee; Self; Becton, Dickinson and Company. J. Petisce: None. D. Saliu: Employee; Self; Becton, Dickinson and Company. |
| Databáze: | OpenAIRE |
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