Rapid expression of COVID-19 proteins by transient expression in tobacco

Autor:	Penelope L Lindsay, Amanda Ackerman, Daniele Rosado, Yinan Jian, Oliver Artz, David A. Jackson, Tara Skopelitis, Ullas V. Pedmale, Munenori Kitagawa
Rok vydání:	2020
Předmět:	2019-20 coronavirus outbreak Coronavirus disease 2019 (COVID-19) viruses Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Pandemic medicine Biology medicine.disease_cause Virology Virus Coronavirus
DOI:	10.1101/2020.12.29.424712
Popis:	In 2020 we suffered from a major global pandemic caused by the SARS-CoV-2 coronavirus. Efforts to contain the virus include the development of rapid tests and vaccines, which require a ready supply of viral proteins. Here we report the production of two SARS-CoV-2 proteins by transient transformation of tobacco, leading to high expression within three days, and subsequent purification of the intact proteins. Such efforts may help to develop testing resources to alleviate the major impacts of this global pandemic.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e2c51e068502695d7807880d309e1ab6 https://doi.org/10.1101/2020.12.29.424712 Zobrazit plný text záznamu