| Autor: |
Wainberg, Milton L., Mann, Claudio G., Norcini Pala, Andrea, McKinnon, Karen, Pinto, Diana, Pinho, Veronica, Cavalcanti, Maria T., Leu, Cheng-Shiun, Guimaraes, Mark D., Mattos, Paulo E., Hughes, Elizabeth, Palinkas, Lawrence A., Otto-Salaj, Laura, Remien, Robert H., Cournos, Francine, PRISSMA Project |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.7916/d8-ftkc-5c32 |
| Popis: |
Objective: Human immunodeficiency virus (HIV) prevention efficacy trials with psychiatric patients have been conducted in research settings in high-resourced countries, establishing short-term efficacy for reducing sexual risk behavior. None has been implemented within systems of care. In the last decade, overcoming this research-to-practice gap has become a focus of implementation science. This paper describes the first and only HIV Prevention intervention trial for psychiatric patients conducted in real-world outpatient psychiatric settings facilitated by trained clinic-based providers. Methods: The HIV Prevention intervention, which uses the Information-Motivation-Behavioral Skills model to achieve sexual risk-reduction, was rigorously adapted to the local context and clinic services' needs. Participants from eight clinics were randomized to HIV Prevention or Health Promotion conditions. Results: HIV Prevention participants showed significant improvement in Information-Motivation-Behavioral domains; in this group, behavioral intentions were associated with significantly fewer unprotected sex occasions, but reduction of unprotected sex occasions was similar in both conditions. Conclusion: Our trial was conducted before implementation studies became widely funded. Transporting an intervention to a new culture or into real-world practice settings may require adaptations. Our results demonstrate that clear guidelines are needed regarding whether to conduct efficacy, effectiveness, and/or implementation research as the most appropriate next step. Clinical trial registration: NCT00881699. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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