Primary adrenal leiomyosarcoma: clinical case and literature review

Autor: N. S. Lukyanov, S. S. Todorov, V. Y. Deribas, S. V. Lukyanov, K. M. Blikyan
Rok vydání: 2021
Předmět:
Zdroj: Endocrine Surgery. 15:36-42
ISSN: 2310-3965
2306-3513
DOI: 10.14341/serg12711
Popis: Adrenal leiomyosarcoma — rare mesenchymal tumor, which is diagnosed most often after it reaches a large size. Primary adrenal leiomyosarcoma is extremely rare: in the English-language literature, only 45 cases were previously reported. We report the case of a 46-year-old man with the formation of the right adrenal gland measuring 12x8x7,5 cm. The patient underwent right-sided adrenalectomy, nephrectomy, and plastic of the inferior vena cava. The phenotype was confirmed by light microscopy and immunohistochemistry. Microscopic examination of the tumor is represented by fusiform and polymorphic cells that form multidirectional bundle structures with a high rate of mitosis. Immunohistochemically, tumor cells were positive for smooth muscle actin, CD-34, CD-117.
Databáze: OpenAIRE