Impact of Community-Onset Methicillin-ResistantStaphylococcus aureusonStaphylococcus aureusBacteremia in a Central Korea Veterans Health Service Hospital
| Autor: | Jung Hyun Jang, Choon Kwan Kim, Mi Na Kim, YounMi Choi, Heungsup Sung, Eunsin Bae |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Meticillin 030106 microbiology Clinical Biochemistry Drug resistance medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Internal medicine medicine 030212 general & internal medicine Typing business.industry SCCmec Biochemistry (medical) General Medicine biochemical phenomena metabolism and nutrition bacterial infections and mycoses medicine.disease Methicillin-resistant Staphylococcus aureus Staphylococcus aureus Bacteremia Multilocus sequence typing business medicine.drug |
| Zdroj: | Annals of Laboratory Medicine. 39:158-166 |
| ISSN: | 2234-3814 2234-3806 |
| DOI: | 10.3343/alm.2019.39.2.158 |
| Popis: | BACKGROUND No study has examined the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in Korean veterans' hospitals. We investigated the microbiological and clinical epidemiology of S. aureus bacteremia at the central Veterans Health Services (VHS) hospital in Korea. METHODS Patients with S. aureus bacteremia were consecutively enrolled from February to August 2015. Bacteremia was classified as hospital-acquired (HA), community-onset healthcare-associated (COHA), or community-acquired (CA). MRSA bacteremia risk factors were analyzed. Species identification, antimicrobial susceptibility, and presence of luk and tst were tested. Staphylococcal cassette chromosome mec (SCCmec) typing, spa sequence typing agr polymorphism typing, and multilocus sequence typing were performed. Biofilm production and δ-hemolysin activity were measured to determine agr function. RESULTS In total, 60 patients were enrolled (30 HA, 23 COHA, and seven CA bacteremia); 44 (73.3%) had MRSA bacteremia (26 HA, 16 COHA, and two CA). MRSA bacteremia occurred more frequently in non-CA patients and those who had received antibiotic treatment within the past month (P |
| Databáze: | OpenAIRE |
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