| Autor: |
Marina Pérez Redondo, Sara Alcántara Carmona, Susana Villar García, Alberto Forteza Gil, Hector Villanueva Fernández, Francisco José Hernández-Pérez, Jose Luis Campo-Cañaveral de la Cruz, Rocío Velasco Calvo, Javier Segovia-Cubero, Beatriz Alonso Menárguez, Francisco del Río Gallegos, Elisabeth Coll, Beatriz Domínguez-Gil Gonzalez, Juan José Rubio Muñoz |
| Rok vydání: |
2020 |
| Popis: |
BackgroundControlled donation after circulatory death (cDCD) has emerged as one of the main strategies for increasing the organ donor pool. Because of the ischemic injury that follows the withdrawal of life-sustaining therapies, hearts from cDCD donors have not been considered for transplantation until recently. The ex-situ perfusion of hearts directly procured from cDCD donors has been used to allow the continuous perfusion of the organ and the assessment of myocardial viability prior to transplantation.Based on our experience with abdominal normothermic regional perfusion in cDCD, we designed a protocol to recover and validate hearts from cDCD donors using thoraco-abdominal normothermic regional perfusion without any ex-situ device.Case presentationWe describe the first case of a cDCD heart transplant performed with this approach in Spain. The donor was a 43-year-old asthmatic female diagnosed with severe hypoxic encephalopathy. She was considered the potential cDCD donor as a suitable candidate for multiorgan procurement including the heart via thoraco-abdominal normothermic regional perfusion. The heart recipient was a 60-year-old male diagnosed with amyloid cardiomyopathy. Cold ischemia time was 55 minutes. The surgery was uneventful.ConclusionsThis case report has revealed the feasibility of evaluating and successfully transplanting cDCD hearts without the need for ex-situ perfusion based on the use of thoraco-abdominal normothermic regional perfusion. It opens up the way for multiorgan donation in cDCD. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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