Acute Cardiovascular Effects of Non-Invasive Electrical Spinal Cord Stimulation: Results from a Pilot Study in Humans
| Autor: | Elena N. Zharova, Dmitry S. Lebedev, Evgeny Shlyakhto, Natalia N. Belyaeva, Tatiana Moshonkina, Svetlana V. Garkina, Evgeny N. Mikhaylov, Andrey V. Kozlenok, Pavel D. Kovzelev |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Heart disease medicine.medical_treatment Pharmaceutical Science Hemodynamics Catheter ablation 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine Genetics medicine Genetics (clinical) Cardiac electrophysiology business.industry Effective refractory period Cardiac arrhythmia medicine.disease Neuromodulation (medicine) 030104 developmental biology Blood pressure Cardiology Molecular Medicine Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiovascular Translational Research. 13:891-893 |
| ISSN: | 1937-5395 1937-5387 |
| DOI: | 10.1007/s12265-020-10014-7 |
| Popis: | We aimed to determine if non-invasive electrical spinal cord stimulation (NIE-SCS) is associated with acute changes in systemic and pulmonary hemodynamics and cardiac electrophysiology at rest. Nine subjects without structural heart disease referred for catheter ablation of cardiac arrhythmia were included. NIE-SCS was performed in each patient at vertebral levels T1, T7, and T11. Higher systolic BP (BPs) was detected during T1 NIE-SCS as compared with baseline (147.9 ± 22.5 vs 135.4 ± 17.4 mmHg; P = 0.02). Atrioventricular nodal effective refractory period (AVN ERP) was shorter during stimulation at T1 and T7, when compared with baseline values (baseline 303.3 ± 15.0 vs 272.0 ± 19.2 for T1 vs 278.0 ± 8.3 ms for T7; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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