Role of arginine, taurine 4 and homocysteine in cardiovascular diseases
| Autor: | L Nittynen, Riitta Korpela, Marja-Leena Nurminen, Heikki Vapaatalo |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Taurine Antioxidant Homocysteine Arginine Vascular disease medicine.medical_treatment General Medicine 030204 cardiovascular system & hematology Biology medicine.disease 3. Good health Amino acid 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology chemistry Internal medicine medicine Plasma homocysteine 030212 general & internal medicine Risk factor |
| Zdroj: | Annals of Medicine. 31:318-326 |
| ISSN: | 1365-2060 0785-3890 |
| DOI: | 10.3109/07853899908995898 |
| Popis: | Arginine, taurine and homocysteine are amino acids which have been shown to affect the risk factors of cardiovascular diseases in humans. Arginine and taurine may protect against cardiovascular diseases while homocysteine may be a risk factor for them. Both arginine and taurine seem to lower blood pressure, arginine may also inhibit atherogenesis, and taurine may have antioxidant properties. However, the evidence of the beneficial effects of arginine and taurine supplementation from human studies is insufficient. Elevated levels of plasma homocysteine may be associated with atherosclerotic and thromboembolic cardiovascular diseases. Supplementation with folic acid seems to be effective in reducing hyperhomocysteinaemia, but there is an insufficient number of studies showing that lowering of homocysteine levels with vitamin supplementation will reduce the risk of cardiovascular diseases. In conclusion, further research is needed to determine the optimal levels for taurine and arginine in the human diet in order to decrease the risk factors for cardiovascular diseases, and to whom supplementation with folic acid should possibly be recommended to reduce hyperhomocysteinaemia. Even though the use of arginine and taurine supplements to reduce cardiovascular risk factors is an interesting possibility, the reported health-promoting effects and the safety of such a supplementation should first be confirmed. |
| Databáze: | OpenAIRE |
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