Poor Reproductive Prognosis in Severe Teratozoospermia with a Predominant Sperm Anomaly/Schlechte Zeugungsfähigkeits-Prognose bei schweren, monomorphen Teratozoospermie-Fällen
| Autor: | M. Ruspa, A. Baglioni, M. Balerna, Ana Piffaretti-Yanez, A. Campana, Maurizio Marchini |
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| Rok vydání: | 2009 |
| Předmět: |
Infertility
Teratospermia Gynecology medicine.medical_specialty Poor prognosis medicine.diagnostic_test business.industry Urology media_common.quotation_subject Semen General Medicine Teratozoospermia Semen analysis medicine.disease Sperm Andrology Endocrinology medicine medicine.symptom Reproduction business media_common |
| Zdroj: | Andrologia. 21:468-475 |
| ISSN: | 1439-0272 0303-4569 |
| DOI: | 10.1111/j.1439-0272.1989.tb02450.x |
| Popis: | A retrospective examination of the semen analyses performed in our clinic from January 1979 to September 1986 revealed that approximately 15% of the patients were affected by severe teratozoospermia (greater than 80% abnormal forms and greater than 5 x 10(6) sperm/ml). In approximately 8% of these cases, a single predominant anomaly (same defect in greater than 50% of the sperm) was reported and confirmed by subsequent analyses (n = 37). The types of monomorphic teratozoospermia encountered in this study included round head (n = 6), amorphous head (n = 16), small head (n = 6), tapering head (n = 2), pin head (n = 1) and midpiece anomaly (n = 6). The clinical data suggest that familial genetic factors are probably involved in round head-monomorphic teratozoospermia, whereas testicular factors may be associated with amorphous head-monomorphic teratozoospermia. No matter what type of monomorphic teratozoospermia, the data in vivo (no pregnancies recorded in the follow-up period ranging from 2-8 years) and in vitro (negative SPAs) suggest a poor prognosis for the couples affected by this syndrome. |
| Databáze: | OpenAIRE |
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