| Autor: |
Melexima Simirea, Cédric Baumann, Michael Bisch, Hélène Rousseau, Paolo Di Patrizio, Sarah Viennet, Stéphanie Bourion-Bédès |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-961623/v1 |
| Popis: |
Background Health-related quality of life (HRQoL) is an important element of patient care and clinical research. The aim of this study was to describe HRQoL changes and identify associated factors during a 6-month follow-up among outpatients starting care for alcohol or opioid dependence. Methods HRQoL was measured at baseline and 3 and 6 months later using the SF-12. Data on sociodemographics, clinical characteristics and patient levels of anxiety and depression were collected using the Hospital Anxiety and Depression Scale (HADS). Repeated-measures analyses were performed to assess factors associated with global HRQoL differences and evolution of HRQoL in both physical and mental scores (PCS and MCS, respectively). Results The mean PCS and MCS scores were initially low at 45.4 (SD=8.6) and 36.0 (SD=10.9), respectively. The improvement in HRQoL was rapid in the first 3-month period, then slower and was even maintained over the subsequent 3-month period. Being employed (p=0.012), having no comorbidities (p=0.0144) and no depression (p=0.0041) were associated with significant differences in the average PCS scores at the 3 time points. Patients who had lower overall HRQoL MCS scores on average were those for whom a medication was initiated (p= 0.0086), as was the case for patients with anxiety (p=0.0001) and depression (p=0.0009). Patients with depression at baseline were also those for whom a significantly greater increase in MCS during the 6 months of follow-up was observed. Conclusion Our findings highlight the importance of screening early psychological distress and considering other factors associated with HRQoL changes after the first 3-month period in SUD outpatients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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