Delayed meconium passage and feed intolerance in neonates with birth weight <1250 g
| Autor: | Arun Soni, Sujit Shrestha, Manoj Modi, Satish Saluja, Sanket Goyal |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty business.industry Obstetrics Incidence (epidemiology) Birth weight General Medicine medicine.disease Enteral administration law.invention Sepsis 03 medical and health sciences fluids and secretions 0302 clinical medicine Meconium Randomized controlled trial law 030225 pediatrics embryonic structures Necrotizing enterocolitis Medicine 030212 general & internal medicine Risk factor business |
| Zdroj: | Current Medicine Research and Practice. 6:12-15 |
| ISSN: | 2352-0817 |
| DOI: | 10.1016/j.cmrp.2016.01.013 |
| Popis: | Background Optimal feeding strategy in preterm neonates is unclear. These neonates are at high risk of feed intolerance (FI) and necrotizing enterocolitis (NEC). Considering this risk, introduction of enteral feeding in these neonates is usually delayed. Delayed passage of meconium has been considered as risk factor for FI. We planned this study with an objective to compare incidence of FI and NEC in neonates who passed meconium early vs those who had delayed passage of meconium. Methods Data of all neonates Results Incidence of FI was 32.5% in early meconium group vs 57.1% in delayed meconium group, adjusted OR (95% CI): 0.37 (0.18, 0.75). Neonates in early meconium group had lesser duration of IV alimentation and reached full enteral feed (180ml/kg/day) earlier. Incidence of NEC, sepsis, and mortality was comparable. Conclusion Early passage of meconium is associated with better feed tolerance, reduced duration of IV alimentation, and earlier establishment of full enteral feed in preterm neonates. Large randomized trials are warranted to evaluate impact of facilitated/scheduled evacuation of meconium on outcomes of preterm neonates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|