Improved and rapid synthesis of new coumarinyl chalcone derivatives and their antiviral activity

Autor:	Erik De Clercq, Christophe Pannecouque, Yogesh T. Naliapara, Jalpa C. Trivedi, Anamik Shah, Kuldip Upadhyay, Jitender Bariwal, Sudhir K. Joshi
Rok vydání:	2007
Předmět:	Chalcone chemistry.chemical_compound chemistry Anti hiv Organic Chemistry Drug Discovery Organic chemistry heterocyclic compounds Biochemistry Combinatorial chemistry
Zdroj:	Tetrahedron Letters. 48:8472-8474
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2007.09.175
Popis:	Two closely structurally related coumarins, 4-hydroxy-8-isopropyl-5-methylcoumarin and 4-hydroxy-6-chloro-7-methylcoumarin were acylated at C-3 and further converted to the respective chalcones and two series of eighteen new compounds, which were evaluated for possible antiviral activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e25620c19de1b470674e73cf7a8cbd6a https://doi.org/10.1016/j.tetlet.2007.09.175 Zobrazit plný text záznamu Full Text from ScienceDirect