Resistive Index for the Evaluation of Renal Damage in Diabetes Mellitus Type 2
| Autor: | Ventsislava Pencheva, Atanas Kundurdgiev, Diyan Genov |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Creatinine
medicine.medical_specialty Proteinuria business.industry Renal damage Urology Renal function 030209 endocrinology & metabolism 030204 cardiovascular system & hematology urologic and male genital diseases medicine.disease Resistive index 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Diabetes mellitus Medicine medicine.symptom business Prospective cohort study Kidney disease |
| Zdroj: | Open Journal of Internal Medicine. :160-166 |
| ISSN: | 2162-5980 2162-5972 |
| DOI: | 10.4236/ojim.2018.82016 |
| Popis: | Background: One of the most common causes of renal impairment and development of chronic kidney disease is diabetes mellitus type 2 (DM 2). The aim of this prospective study was to determine the role of Resistive Index (RI) as a non-invasive marker for the evaluation of renal impairment in patients with DM 2. Material and Methods: 47 patients with DM 2 in mean age 62.66 ± 10.081 years were included in the study for the period of one year. All of them were with well-compensated diabetes mellitus (HbA1c 0.05 for all). There was significant difference between the groups according to serum creatinine (p = 0.026), GFR (p = 0.044) and the degree of proteinuria (p = 0.001). There was a positive correlation between RI and serum creatinine (r = 0.418; p = 0.001) and between RI and proteinuria (r = 0.396; p = 0.004). A negative correlation relationship between RI and GFR values was found (r = –0.413; p = 0.011). Conclusions: RI may be used as an indicator for the assessment of the severity of renal impairment in patients with DM 2. It correlates well with serum creatinine, GFR and proteinuria, which are proven biochemical parameters indicating the degree of renal damage in patients with DM 2. |
| Databáze: | OpenAIRE |
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