| Popis: |
A case-control pharmaco-epidemiological study, aimed to identify the drug class and/or duration of treatments causing hyposideremia, was carried out. For this, the prescription medicines of all patients addmited to a Internal Medicine service, for various indications, along a 1-year period (2019), were recorded and, ultimately, its association to hyposideremia analyzed. As a result, it was identified several drugs associated with alterations in serum iron levels: acetylcysteine, apixaban and edoxaban, which would increase the risk of hyposideremia. On the contrary, we found that allopurinol, duloxetine and simvastatin would protect against the appearance of hyposideremia. These drugs, alone or in combination with different pathologies, would be capable of inducing, and on dependence of the duration of treatment and/or of the concomitant pathology, hyposideremia, iron deficiency and, in certain cases, anemia constituting a major health problem. |
