MORPHOFUNCTIONAL STATE OF PLACENTA UNDER MYCOPLASMA INFECTION
| Autor: | Viktoriya Obuhova, O. V. Kozharskaya, E Nagovitsyna, Olga Lebedko, Galina Evseeva, Natalya Ivakhnishina, Stefaniya Suprun, Olga Ostrovskaya, D. V. Musatov, Marina Vlasova |
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| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
030219 obstetrics & reproductive medicine business.industry Mycoplasma medicine.disease_cause Microbiology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Placenta Pediatrics Perinatology and Child Health Medicine 030212 general & internal medicine business |
| Zdroj: | Bulletin physiology and pathology of respiration. 1:43-49 |
| ISSN: | 1998-5029 |
| DOI: | 10.12737/article_5b9758eab95055.27382492 |
| Popis: | Literature data on the ethiopathogenetic role of Ureaplasma species, Mycoplasma hominis in the development of premature delivery is contradictory due to the fact that Mycoplasma may be part of the normal microflora of women of reproductive age. The article is aimed to reveal the peculiarities of morphofunctional state of the placentas infected with Mycoplasma. The placentas were obtained from women whose pregnancy ended prematurely. Morphological, histological and molecular genetic study of 34 placentas from maternity patients with premature delivery was performed. Molecular genetic study was carried out by real-time PCR. Ureaplasma spp. was detected as a part of mono- and mixed infections in a concentration of 10*2 to 10*6 GE/mL in 32.3% of cases. Mycoplasma hominis was detected in 23.5% of cases, in a concentration of 10*3 to 10*6 GE/mL. Inflammatory changes in the membranes and placenta were revealed in all cases of Ureaplasma spp. detection as a monoinfection regardless of the degree of bacterial load, which confirms the belief about the pathogenetic role of Ureaplasma spp. in the process of reproductive disorders formation. |
| Databáze: | OpenAIRE |
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