Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106

Autor:	Timo Heinrich, Carl Peterson, Richard Schneider, Sakshi Garg, Daniel Schwarz, Jakub Gunera, Anita Seshire, Lisa Kötzner, Sarah Schlesiger, Djordje Musil, Heike Schilke, Benjamin Doerfel, Patrizia Diehl, Pia Böpple, Ana R. Lemos, Pedro M. F. Sousa, Filipe Freire, Tiago M. Bandeiras, Emma Carswell, Nicholas Pearson, Sameer Sirohi, Mollie Hooker, Elisabeth Trivier, Rebecca Broome, Alexander Balsiger, Abigail Crowden, Christian Dillon, Dirk Wienke
Rok vydání:	2022
Předmět:	Drug Discovery Molecular Medicine
Zdroj:	Journal of Medicinal Chemistry. 65:9206-9229
ISSN:	1520-4804 0022-2623
DOI:	10.1021/acs.jmedchem.2c00403
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e22c0126effbafdbcab44017975b2c5d https://doi.org/10.1021/acs.jmedchem.2c00403 Zobrazit plný text záznamu