2-Aminooxazoles as novel dienophiles in the inverse demand Diels–Alder reaction with 1,2,4-triazines

Autor:	Guda Mallikarjuna Reddy, Alexey P. Krinochkin, Dmitry S. Kopchuk, Yaroslav K. Shtaitz, Grigory V. Zyryanov, Grigory A. Kim, Igor A. Khalymbadzha, Oleg N. Chupakhin, Pavel A. Slepukhin, Igor S. Kovalev, I. N. Ganebnykh, Valery N. Charushin
Rok vydání:	2021
Předmět:	Reaction mechanism chemistry.chemical_compound Diene Computational chemistry Chemistry Moiety General Chemistry Inverse demand function Diels–Alder reaction Oxazole
Zdroj:	Mendeleev Communications. 31:542-544
ISSN:	0959-9436
Popis:	High temperature coupling of 6-aryl-5-cyano-3-(pyridin-2-yl)-1,2,4-triazines with 2-amino-4-aryloxazoles proceeds as the inverse demand Diels–Alder reaction between the oxazole moiety as dienophile and the 1,2,4-triazine moiety as diene to construct new 4,5-diaryl-6-cyano-3-hydroxypyridin-2-yl fragment. A reaction mechanism is proposed, and the structure of the key-product is proved by the X-ray diffraction analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e226b244762b57e4e1e7f50c4a0ef0ee https://doi.org/10.1016/j.mencom.2021.07.035 Zobrazit plný text záznamu Full Text from ScienceDirect