OXIDATIVE STRESS AND ANTIOXIDANTS WITH EMPHASIS ON AGEING (Review Article)

Autor: ANAND ANJALI, EKA LOMINADZE, GURAM MATITASHVILI, NIKA KAPANADZE, TEKLE DARTSIMELIA, TINATIN TKEMALADZE
Rok vydání: 2022
Zdroj: EXPERIMENTAL & CLINICAL MEDICINE GEORGIA.
ISSN: 2667-9736
1512-0392
DOI: 10.52340/jecm.2022.02.14
Popis: Numerous theories have been postulated to understand the process of aging. One of them links degenerative senescence to reactive oxygen species (ROS), which are natural byproducts of oxygen metabolism. Understanding and supporting this theory may be of great importance due to number of reasons. Firstly, there are well-established risk factors that can increase the production of ROS in our body. Secondly, there are different types of antioxidants that can neutralize toxic effects of ROS. Examples of antioxidants include natural enzymes produced in our body, as well as certain exogenous supplements. Moreover, antioxidant supplementation is already offered by some facilities as a hope to decrease age-related complications. Therefore, it is crucial to understand, how ROS is involved in the process of aging and if there is any evidence how alteration in ROS and antioxidants levels influence the process of ageing.
Databáze: OpenAIRE