Intermediary metabolism in the dauer larva of the nematode Caenorhabditis elegans—II. The glyoxylate cycle and fatty-acid oxidation

Autor:	Veronica B. O'Riordan, Ann M. Burnell
Rok vydání:	1990
Předmět:	Physiology fungi Glyoxylate cycle Dehydrogenase General Medicine Isocitrate lyase Biology Dauer larva biology.organism_classification Biochemistry Citric acid cycle Metabolic pathway Molecular Biology Beta oxidation Caenorhabditis elegans
Zdroj:	Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 95:125-130
ISSN:	0305-0491
Popis:	1. 1. The activities of the enzymes of the glyoxylate cycle and of the β-oxidation pathway were compared in the dauer larva and the adult stages of C. elegans. 2. 2. The relative rates of NADP isocitrate dehydrogenase (TCA cycle) and isocitrate lyase (glyoxylate cycle) in adult and dauer larvae indicate the increased importance of the glyoxylate cycle in dauer larvae. 3. 3. High levels of the β-oxidation enzymes acyl-CoA dehydrogenase, enoyl-CoA hydratase and acetyl-CoA acetyltransferase were observed in both adult and dauer fractions, the relative levels of activity being lower in the dauers. 4. 4. These data demonstrate the importance of lipid stores as an energy reserve for the non-feeding dauer larva.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e1e70a50ee9517a8dcd35a9f0a0caffd https://doi.org/10.1016/0305-0491(90)90258-u Zobrazit plný text záznamu