Tin-free radical chemistry: intramolecular addition of alkyl radicals to aldehydes and ketones

Autor:	Louis Fensterbank, Priscille Devin, Max Malacria
Rok vydání:	1999
Předmět:	chemistry.chemical_classification Ketone Alkene Radical Organic Chemistry Triethylborane Tributyltin hydride Photochemistry Biochemistry Aldehyde Radical cyclization chemistry.chemical_compound chemistry Drug Discovery Radical initiator
Zdroj:	Tetrahedron Letters. 40:5511-5514
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(99)01072-2
Popis:	The radical cyclization of several ω-iodoaldehydes and a ketone can be accomplished without the use of tributyltin hydride. Triethylborane in presence of oxygen or light from a sun lamp can serve as a radical initiator and terminator. In these conditions, a 5-exo-trig cyclization on an aldehyde is faster than on an alkene.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e1e33c2d1817893162fbebe3f01baa7d https://doi.org/10.1016/s0040-4039(99)01072-2 Zobrazit plný text záznamu Full Text from ScienceDirect