Optic Neuritis: Visual Outcome and Risk Factors for the Development of Multiple Sclerosis in Western Turkey

Autor:	Figen Gökçay, Neşe Çelebisoy, Halil Güllüoğlu, Timur Köse, Ayşe Nur Yüceyar, Ayse Sagduyu Kocaman
Rok vydání:	2011
Předmět:	medicine.medical_specialty Pediatrics medicine.diagnostic_test business.industry Multiple sclerosis Magnetic resonance imaging Mean age medicine.disease Surgery Ophthalmology medicine.anatomical_structure medicine Optic neuritis Neurology (clinical) business Optic disc
Zdroj:	Neuro-Ophthalmology. 35:115-120
ISSN:	1744-506X 0165-8107
DOI:	10.3109/01658107.2011.580888
Popis:	Optic neuritis (ON) is highly associated with multiple sclerosis (MS) and conversion rate has been reported to be around 50% over a period of 15 years. We revised the risk factors for developing MS after an attack of ON, in western Turkey. One hundred and twenty-four patients with acute unilateral ON, who were on follow-up for at least 5 years (range 62 to180 months, mean 85 months) were enrolled in the study. Gender, age at onset, seasonal occurrence, severity of visual loss, presence of pain, optic disc appearance, treatment, degree of recovery, presence or absence of lesions on magnetic resonance imaging (MRI) during the initial ON attack and recurrence were considered. Of the 124 patients, 89 (71.8%) were women, 35 (28.2%) were men, with a mean age of 28.7 ± 8.6 years at the time of the initial ON attack. During follow-up, 70 patients (56.5%) developed MS within 17.14 months, ranging from 1 to 125 months. Female gender (p = 0.021), experiencing the attack before 40 years of age (p = 0.02), normal-appe...
Databáze:	OpenAIRE
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