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Objective: This study aims to analyze the correlation between the initial creatinine and the nadir creatinine values and the risk of chronic kidney disease in patients with posterior urethral valves. Materials and methods: The medical records of all patients with PUV treated in the surgery department of The Emergency Children’s Hospital “Marie Curie” between January 2007 – January 2020 were analyzed. The age at presentation, serum creatinine, nadir creatinine, and glomerular filtration rate were noted. The patients were divided in three groups based on the marker values. Results: 77 patients were studied. The high-risk group (13%) was represented by patients with initial creatinine and nadir creatinine >0.85 mg/dL, with 100% progression to CKD. The low-risk group (33%) showed a very low development of renal insufficiency for values of |