| Autor: |
Liam Gibson, Audrey Lustig, Megan Poehler, Alex James, Reuben McGregor, Nicole J. Moreland |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.1101/2021.06.13.21258857 |
| Popis: |
Estimating the longevity of an individual's immune response to the Sars-Cov-2 virus is vital for future planning, particularly of vaccine requirements. Neutralising antibodies (Nabs) are increasingly being recognised as a correlate of protection and whilst there are many studies which follow the response of a cohort of people, each study alone is not enough to predict the long term response. Studies use different assays to measure Nabs making them hard to combine. We present a modelling method which can combine multiple datasets and can be updated as more detailed data becomes available. Combining data from six published datasets we predict that after a short period of rapid decay the half-life of the NAb response is approximately one year giving optimism that the response will be long-lived. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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