Bioactive Composites Reinforced with Inorganic Glasses and Glass–Ceramics for Tissue Engineering Applications
| Autor: | Ricardo A. Pires, João F. Mano, Álvaro J. Leite, Alexandre António Antunes Barros, Rui L. Reis |
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| Rok vydání: | 2014 |
| Předmět: |
chemistry.chemical_classification
Materials science Biocompatibility 02 engineering and technology Polymer 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Bone bonding Membrane Tissue engineering chemistry visual_art visual_art.visual_art_medium Ceramic Composite material 0210 nano-technology Bone regeneration Inorganic particles |
| Zdroj: | Springer Series in Biomaterials Science and Engineering ISBN: 9783642539794 |
| DOI: | 10.1007/978-3-642-53980-0_10 |
| Popis: | Bioactive composites, prepared by the combination of glasses or glass–ceramics with natural or synthetic polymers or blends, have been extensively exploited in bone tissue engineering. Their bioactive character is usually derived from the glass or glass–ceramic phase and is one of the most relevant properties to generate bone bonding. Herein we focus on the development of bioactive composite structures that target tissue engineering applications, with special emphasis on bone regeneration. Some concepts, e.g., bioactivity and biocompatibility, are initially introduced, followed by a description of the synthetic approaches that have been reported for the preparation of bioactive inorganic glasses or glass–ceramics. Different strategies to compound these inorganic particles with polymeric phases are detailed, spanning from conventional methodologies and wet spinning to rapid prototyping. Finally, a series of systems that have been developed for bone tissue engineering are described (including injectable systems, 3D scaffolds, membranes, and biomimetic layer-by-layer structures), as well as their in vitro biological response. |
| Databáze: | OpenAIRE |
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