Atherosclerosis profile and microalbuminuria in essential hypertension
| Autor: | Jesus Calviño, Carlos Calvo, R. Romero, Francisco Gude, D. Sanchez-Guisande |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Proteinuria Ambulatory blood pressure business.industry Population Hemodynamics medicine.disease Essential hypertension Endocrinology Blood pressure Nephrology Diabetes mellitus Internal medicine medicine Cardiology Microalbuminuria medicine.symptom education business |
| Zdroj: | American Journal of Kidney Diseases. 34:996-1001 |
| ISSN: | 0272-6386 |
| DOI: | 10.1016/s0272-6386(99)70003-x |
| Popis: | Whether microalbuminuria (MA) is the result of intrarenal hemodynamic changes induced by increased systemic blood pressure (BP) or a marker of capillary leakiness at the glomerular level that reflects more generalized atherosclerotic vascular damage is still debated. To address this question, 319 patients without diabetes, 154 men and 165 women aged 57 ± 8.6 years (range, 37 to 73 years), but with essential hypertension (EH) never treated with drugs were enrolled onto the study. Using a multiple linear regression analysis, we analyzed the prevalence of MA and its relationship with BP level as well as with other risk factors for the development of atherosclerosis. MA was present in 40% of the population studied. A univariable analysis of ambulatory BP monitoring measurements showed that only 24-hour systolic BP ( P = 0.04), daytime systolic BP ( P = 0.02), and 24-hour daytime and nighttime systolic BP load ( P P P P P |
| Databáze: | OpenAIRE |
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