Reaction of Methyl Diazoacetate with Amines Catalyzed by Ru2(OAc)4Cl

Autor:	R. Z. Biglova, Rimma M. Sultanova, A. V. Maidanova, Vladimir A. Dokichev, A. D. Bakeeva
Rok vydání:	2010
Předmět:	Chemistry Yield (chemistry) Organic Chemistry Glycine Regioselectivity Organic chemistry Medicinal chemistry Catalytic decomposition Catalysis
Zdroj:	Russian Journal of Organic Chemistry. 46:1461-1465
ISSN:	1608-3393 1070-4280
Popis:	Reactions of primary and secondary amines with methyl diazoacetate in the presence of Ru2(OAc)4Cl gave the corresponding N-substituted glycine methyl esters in almost quantitative yield. Catalytic decomposition of methyl diazoacetate generates methoxycarbonylcarbene which is inserted into the N-H bond of amines with high regioselectivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e194412fc420523ca19815ae0d7ea468 https://doi.org/10.1134/s1070428010100039 Zobrazit plný text záznamu Plný text ve formátu PDF